Transcriptome alterations of mitochondrial and coagulation function in schizophrenia by cortical sequencing analysis

Table 2 SCZCGs associated with CORUM complexes and its GO characterization.

Complex name in CORUM	SCZCGs (^:over-expressed gene, *:under-expressed gene)	GO characterization
Spliceosome	LSM4, CDK12, PPIL3^, THOC5, EFTUD2	RNA splicing and binding
55S ribosome, mitochondria	MRPL52, MRPL15, MRPL48, MRPL43	Protein biosynthesis, mitochondria matrix
39S ribosomal subunit, mitochondria	MRPL52, MRPL15, MRPL48, MRPL43	Protein biosynthesis, mitochondria matrix
VEGF transcriptional complex	APEX1, CITED1, STAT3*	Regulation of transcription
PLCB3-PARD3-PARD6A complex	PLCB3^, PARD3^, PARD6A*	Regulation of transcription, second messenger-mediated signaling
Nop56p associated pre-rRNA complex	SLC25A5, RPS14^, TCOF1	Ribosome biogenesis
AP3-BLOC1 complex	AP3S2, SNAP1N, DTNBP1*	Protein targeting and transport

ISSN: 1471-2164