Table 3 Functional annotation of MCL in SCZCGs by DAVID.
Cluster No.(cluster genes >30) (SCZCGs/cluster genes) | SCZCGs in gene modules by MCL (^:over-expressed gene, *:under-expressed gene) | Functional annotations by DAVID |
|---|---|---|
QUERY Cluster: 1 (21/215) | APEX1*,C1orf86*,DHRS7B*, DTNBP1*,EPO*,GFRA2*, KATNAL1^,NPRL3*,NUB1*, PCNA*,PLK3*,SHKBP1*,SMG9*, SPNS1*,STRADA*,SUPT3H^, TP53*,TREX1*,TTLL5*,VPS52*, ZNF174* | Regulation of transcription, DNA-dependent Regulation of RNA metabolic process |
QUERY Cluster: 2 (16/154) | CAMTA2*,CDC42EP2*,FBXL19*,FOXN3*,KRT81*,MEF2C^,MPST*,MYOCD*,MYPOP*,NCOR2*, NFKBIZ*,PLA2G4C*,SIN3A^, SPARCL1*,SQRDL*,ZNF200* | Transcription regulator activity DNA binding Phosphoprotein |
QUERY Cluster: 3 (6/83) | ADCY10^,GOLGA7*,LMNA*, MASTL*,ODF2*,PCNXL3* | Cytoskeleton Spliceosome Methylation Telomere maintenance ATP binding Regulation of apoptosis MAPK signaling pathway ErbB signaling pathway Cell cycle Actin filament binding Protein kinase activity |
QUERY Cluster: 7 (3/40) | C16orf59*,PRKCZ^,TRIM4^ | Protein kinase cascade ATP binding Tyrosine-protein kinase Phosphate metabolic process |
QUERY Cluster: 9 (3/31) | LMO3^,MCM10^,SDCBP2* | DNA replication Cell cycle ATP binding |
QUERY Cluster: 10 (3/31) | FN1*,IGLL5*,ST14* | Hemostasis |