Figure 5
From: Homopharma: A new concept for exploring the molecular binding mechanisms and drug repurposing
The in vitro enzymatic profiling results. (A) Quercetin and its target kinases. (B) JMY51 and its target kinases. (C) JMY65 and its target kinases. (D) JMY84 and its target kinases. The red and blue points mean the bioactivities are ≤ 1 μM and ≤ 10 μM, respectively. Kinome tree representation is prepared using Kinome Mapper (http://www.reactionbiology.com/apps/kinome/mapper/LaunchKinome.htm). (E) The in vitro enzymatic profiling results of 32 protein kinases and four flavonoid derivatives. The green and dark denote the inhibition efficiency from high to low.