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Table 2 Performance of MHC2MIL(fl) compared to MHCMIR(9) and MHCMIR(11). For each allele, the largest value is displayed in boldface.

From: MHC2MIL: a novel multiple instance learning based method for MHC-II peptide binding prediction by considering peptide flanking region and residue positions

allele MHCMIR(9) MHCMIR(11) MHC2MIL(fl)
HLA-DPA1_01-DPB1_0401 0.772 0.780 0.778
HLA-DPA1_0103-DPB1_0201 0.782 0.792 0.790
HLA-DPA1_0201-DPB1_0101 0.810 0.811 0.817
HLA-DPA1_0201-DPB1_0501 0.784 0.790 0.791
HLA-DPA1_0301-DPB1_0402 0.820 0.832 0.832
HLA-DPB1_0301-DPB1_0401 0.785 0.782 0.791
HLA-DQA1_0101-DQB1_0501 0.763 0.761 0.768
HLA-DQA1_0102-DQB1_0602 0.751 0.760 0.763
HLA-DQA1_0301-DQB1_0302 0.666 0.665 0.672
HLA-DQA1_0401-DQB1_0402 0.732 0.721 0.737
HLA-DQA1_0501-DQB1_0201 0.772 0.758 0.779
HLA-DQA1_0501-DQB1_0301 0.804 0.800 0.809
HLA-DRB1_0101 0.770 0.789 0.786
HLA-DRB1_0301 0.793 0.805 0.808
HLA-DRB1_0401 0.738 0.735 0.741
HLA-DRB1_0404 0.793 0.773 0.791
HLA-DRB1_0405 0.790 0.784 0.792
HLA-DRB1_0701 0.809 0.819 0.819
HLA-DRB1_0802 0.700 0.717 0.712
HLA-DRB1_0901 0.730 0.723 0.733
HLA-DRB1_1101 0.831 0.825 0.834
HLA-DRB1_1302 0.736 0.741 0.745
HLA-DRB1_1501 0.752 0.767 0.765
HLA-DRB3_0101 0.749 0.740 0.756
HLA-DRB4_0101 0.787 0.776 0.787
HLA-DRB5_0101 0.796 0.792 0.803
average AUC 0.770 0.771 0.777