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Table 3 Performance of MHC2MIL(fl) compared to MHC2MIL(fl_fpl). For each allele, the largest value is displayed in boldface.

From: MHC2MIL: a novel multiple instance learning based method for MHC-II peptide binding prediction by considering peptide flanking region and residue positions

allele

MHC2MIL(fl)

MHC2MIL(fl_fpl)

HLA-DRB1_0101

0.786

0.745

HLA-DRB1_0301

0.808

0.765

HLA-DRB1_0401

0.741

0.697

HLA-DRB1_0404

0.791

0.771

HLA-DRB1_0405

0.792

0.737

HLA-DRB1_0701

0.819

0.783

HLA-DRB1_0802

0.712

0.688

HLA-DRB1_0901

0.733

0.692

HLA-DRB1_1101

0.834

0.757

HLA-DRB1_1302

0.745

0.708

HLA-DRB1_1501

0.765

0.718

HLA-DRB3_0101

0.756

0.709

HLA-DRB4_0101

0.787

0.760

HLA-DRB5_0101

0.803

0.746

average AUC

0.777

0.734

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BMC Genomics

ISSN: 1471-2164

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