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Table 4 Performance of MHC2MIL(fl) compared to MHC2MIL(fl+kp). For each allele, the largest value is displayed in boldface.

From: MHC2MIL: a novel multiple instance learning based method for MHC-II peptide binding prediction by considering peptide flanking region and residue positions

allele MHC2MIL(fl) MHC2MIL(fl+kp)
HLA-DPA1_01-DPB1_0401 0.778 0.791
HLA-DPA1_0103-DPB1_0201 0.790 0.808
HLA-DPA1_0201-DPB1_0101 0.817 0.834
HLA-DPA1_0201-DPB1_0501 0.791 0.805
HLA-DPA1_0301-DPB1_0402 0.832 0.846
HLA-DPB1_0301-DPB1_0401 0.791 0.790
HLA-DQA1_0101-DQB1_0501 0.768 0.781
HLA-DQA1_0102-DQB1_0602 0.763 0.769
HLA-DQA1_0301-DQB1_0302 0.672 0.706
HLA-DQA1_0401-DQB1_0402 0.737 0.774
HLA-DQA1_0501-DQB1_0201 0.779 0.810
HLA-DQA1_0501-DQB1_0301 0.809 0.817
HLA-DRB1_0101 0.786 0.787
HLA-DRB1_0301 0.808 0.803
HLA-DRB1_0401 0.741 0.732
HLA-DRB1_0404 0.791 0.782
HLA-DRB1_0405 0.792 0.785
HLA-DRB1_0701 0.819 0.823
HLA-DRB1_0802 0.712 0.716
HLA-DRB1_0901 0.733 0.735
HLA-DRB1_1101 0.834 0.838
HLA-DRB1_1302 0.745 0.734
HLA-DRB1_1501 0.765 0.763
HLA-DRB3_0101 0.756 0.757
HLA-DRB4_0101 0.787 0.792
HLA-DRB5_0101 0.803 0.808
average AUC 0.777 0.784