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Table 7 Comparisons of ARB, SMM-align, PROPRED, MHC2SK, NN-algin and MHC2MIL on DR. For each allele, the largest value is displayed in boldface.

From: MHC2MIL: a novel multiple instance learning based method for MHC-II peptide binding prediction by considering peptide flanking region and residue positions

allele ARB SMM-align PROPRED MHC2SK NN-align MHC2MIL(+2)
HLA-DRB1_0101 0.710 0.756 0.692 0.792 0.763 0.792
HLA-DRB1_0301 0.728 0.808 0.669 0.812 0.829 0.809
HLA-DRB1_0401 0.668 0.721 0.711 0.726 0.734 0.736
HLA-DRB1_0404 0.681 0.789 0.753 0.791 0.803 0.786
HLA-DRB1_0405 0.716 0.767 0.742 0.783 0.794 0.792
HLA-DRB1_0701 0.736 0.796 0.750 0.827 0.811 0.825
HLA-DRB1_0802 0.649 0.689 0.641 0.719 0.698 0.718
HLA-DRB1_0901 0.654 0.696 - 0.744 0.713 0.736
HLA-DRB1_1101 0.777 0.829 0.779 0.844 0.847 0.843
HLA-DRB1_1302 0.667 0.754 0.577 0.729 0.732 0.746
HLA-DRB1_1501 0.696 0.741 0.703 0.771 0.756 0.770
HLA-DRB3_0101 0.678 0.780 - 0.759 0.798 0.762
HLA-DRB4_0101 0.747 0.762 - 0.809 0.789 0.797
HLA-DRB5_0101 0.697 0.776 0.711 0.807 0.795 0.811
average AUC 0.700 0.762 0.703 0.780 0.776 0.780