MHC2MIL: a novel multiple instance learning based method for MHC-II peptide binding prediction by considering peptide flanking region and residue positions

Table 7 Comparisons of ARB, SMM-align, PROPRED, MHC2SK, NN-algin and MHC2MIL on DR. For each allele, the largest value is displayed in boldface.

allele	ARB	SMM-align	PROPRED	MHC2SK	NN-align	MHC2MIL(+2)
HLA-DRB1_0101	0.710	0.756	0.692	0.792	0.763	0.792
HLA-DRB1_0301	0.728	0.808	0.669	0.812	0.829	0.809
HLA-DRB1_0401	0.668	0.721	0.711	0.726	0.734	0.736
HLA-DRB1_0404	0.681	0.789	0.753	0.791	0.803	0.786
HLA-DRB1_0405	0.716	0.767	0.742	0.783	0.794	0.792
HLA-DRB1_0701	0.736	0.796	0.750	0.827	0.811	0.825
HLA-DRB1_0802	0.649	0.689	0.641	0.719	0.698	0.718
HLA-DRB1_0901	0.654	0.696	-	0.744	0.713	0.736
HLA-DRB1_1101	0.777	0.829	0.779	0.844	0.847	0.843
HLA-DRB1_1302	0.667	0.754	0.577	0.729	0.732	0.746
HLA-DRB1_1501	0.696	0.741	0.703	0.771	0.756	0.770
HLA-DRB3_0101	0.678	0.780	-	0.759	0.798	0.762
HLA-DRB4_0101	0.747	0.762	-	0.809	0.789	0.797
HLA-DRB5_0101	0.697	0.776	0.711	0.807	0.795	0.811
average AUC	0.700	0.762	0.703	0.780	0.776	0.780

ISSN: 1471-2164