TY - JOUR AU - Merdad, Adnan AU - Karim, Sajjad AU - Schulten, Hans-Juergen AU - Jayapal, Manikandan AU - Dallol, Ashraf AU - Buhmeida, Abdelbaset AU - Al-Thubaity, Fatima AU - GariI, Mamdooh A. AU - Chaudhary, Adeel GA AU - Abuzenadah, Adel M. AU - Al-Qahtani, Mohammed H. PY - 2015 DA - 2015/01/15 TI - Transcriptomics profiling study of breast cancer from Kingdom of Saudi Arabia revealed altered expression of Adiponectin and Fatty Acid Binding Protein4: Is lipid metabolism associated with breast cancer? JO - BMC Genomics SP - S11 VL - 16 IS - 1 AB - Breast cancer incidence rates are increasing at an alarming rate among Saudi Arabian females. Most molecular genetic discoveries on breast cancer and other cancers have arisen from studies examining European and American patients. However, possibility of specific changes in molecular signature among cancer patients of diverse ethnic groups remains largely unexplored. We performed transcriptomic profiling of surgically-resected breast tumors from 45 patients based in the Western region of Saudi Arabia using Affymetrix Gene 1.0 ST chip. Pathway and biological function-based clustering was apparent across the tissue samples. SN - 1471-2164 UR - https://doi.org/10.1186/1471-2164-16-S1-S11 DO - 10.1186/1471-2164-16-S1-S11 ID - Merdad2015 ER -