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Table 1 Next-generation run statistics for breast cancer exomes.

From: Characterization of familial breast cancer in Saudi Arabia

  case_193 case_195 case_264 case_320 case_573 case_574 case_903
Total reads 108,381,083 84,054,514 95,591,607 89,014,487 107,417,081 89,456,100 62,675,973
Mappable reads (%) 73% 67% 72% 73% 78% 64% 78%
Mappable yield (bp) 3,958,042,800 2,795,592,150 3,425,085,950 3,231,704,750 4,145,428,250 2,865,812,200 2,459,039,800
On-target yield (bp) (%) 46% 61% 74% 47% 63% 68% 52%
Coverage of target region (>10x) 71.24 67.68 67.21 64.93 80.59 70.16 64.64
Mean read depth of targeted region 34.63 33.02 45.09 28.08 49.87 37.42 24.14
Mean read depth of called variants 36.54 72.34 68.94 39.41 56.47 44.61 33.35
Number of high quality variants 23959 1788 5823 10019 18691 14113 9623
Number of missense, nonsense, splice, and indel variants 1861 154 352 619 1240 1035 616
Number of filtered damaging rare variants 53 6 21 39 105 91 45
Number of filtered damaging novel variants 141 46 108 80 116 129 71
Number of filtered damaging novel indels 85 38 129 55 54 38 123