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Figure 3 | BMC Genomics

Figure 3

From: Exome Sequencing of Normal and Isogenic Transformed Human Colonic Epithelial Cells (HCECs) Reveals Novel Genes Potentially Involved in the Early Stages of Colorectal Tumorigenesis

Figure 3

Validation of “deleterious” INCENP variants in ICT series. Predicted “deleterious” mutation p.M506T was confirmed by Sanger sequencing of PCR products from 1CT series. c. T1517>C mutation (highlighted in red box) was detected in all 1CT series as well as the pre-immortalized HCEC1 cells and it occurs at a highly conserved position.

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