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Figure 2 | BMC Genomics

Figure 2

From: Use of Both Cumulus Cells’ Transcriptomic Markers and Zona Pellucida Birefringence to Select Developmentally Competent Oocytes in Human Assisted Reproductive Technologies

Figure 2

Main candidate genes differentially expressed in CCs and involved in both cell and ZP morphologies as revealed by IPA software. (Red): overexpressed genes. (Green): underexpressed genes. (Gray): ZP genes. Genes are CASP9 (caspase 9), CCNA2 (cyclin A2), RAN (RAN, member RAS oncogene family), CDKN1A (cyclin-dependent kinase inhibitor 1A), CYP11A1 (cytochrome P450, family 11, subfamily A, polypeptide 1), GLB1 (galactosidase, beta 1), HBA1/HBA2 (hemoglobin, alpha 1/ hemoglobin, alpha 2), HBB (hemoglobin, beta), HDAC2 (histone deacetylase 2), HSP90B1 (heat shock protein 90, beta, member 1), LAMB1 (laminin, beta 1), PRDX2 (peroxiredoxin 2), SGCB (sarcoglycan, beta), TIE1 (tyrosine kinase with immunoglobulin-like and EGF-like domains 1), ZP1 (zona pellucida glycoprotein 1 (sperm receptor)), ZP2 (zona pellucida glycoprotein 2 (sperm receptor)), ZP3 (zona pellucida glycoprotein 3 (sperm receptor)), and ZPBP (zona pellucida binding protein).

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