Figure 5

Enrichment of charged amino acids in USRs. The probability to observe a charged amino acid in the real USRs is compared to the probability to observe it before random peak positions (details in the Methods section: Quantifying the enrichment of charged amino acids in USRs). The probabilities in random are average values over all randomizations. Standard deviations and p-values are also presented. (A) The probability to observe a positively charged amino acid in real and random USRs for the 11 cases that exhibited a significant p-value (2 datasets of P. falciparum; 8 datasets of S. cerevisiae; and one of D. melanogaster). (B) The probability to observe a negatively charged amino acid in real and random USRs for the 4 cases that exhibited a significant p-value (2 datasets of H. sapiens, one datasets of S. cerevisiae and one datasets of D. melanogaster) (C) The probability to observe a negatively charged amino acid in real and random USRs for the 9 cases where the probability was significantly higher in random than in the real USRs (4 datasets of P. falciparum; one dataset of A. thaliana, one dataset of S. pombe; 2 datasets of S. cerevisiae and one of C. elegans).