Skip to main content

Table 2 Top 10 most significant regulatory edges in the KEGG regulatory gene set network.

From: A method for developing regulatory gene set networks to characterize complex biological systems

Gene set 1 name

Gene set 2 name

P-value

Cell cycle

Cytokine-cytokine receptor interaction

6.46E-75

Cell cycle

Pathways in cancer

5.31E-55

Cell cycle

Toll-like receptor signaling pathway

1E-42

Cell cycle

Focal adhesion

2.22E-36

Cell cycle

Leishmania infection

2.63E-33

Hedgehog signaling pathway

Basal cell carcinoma

3.08E-33

p53 signaling pathway

Cytokine-cytokine receptor interaction

3.38E-33

RIG-I-like receptor signaling pathway

Toll-like receptor signaling pathway

3.39E-33

Cell cycle

Hematopoietic cell lineage

8.26E-33

Cell cycle

Jak-STAT signaling pathway

1.08E-31

  1. The regulatory relationship is gene set 1 regulates gene set 2.