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Table 2 Top 10 most significant regulatory edges in the KEGG regulatory gene set network.

From: A method for developing regulatory gene set networks to characterize complex biological systems

Gene set 1 name Gene set 2 name P-value
Cell cycle Cytokine-cytokine receptor interaction 6.46E-75
Cell cycle Pathways in cancer 5.31E-55
Cell cycle Toll-like receptor signaling pathway 1E-42
Cell cycle Focal adhesion 2.22E-36
Cell cycle Leishmania infection 2.63E-33
Hedgehog signaling pathway Basal cell carcinoma 3.08E-33
p53 signaling pathway Cytokine-cytokine receptor interaction 3.38E-33
RIG-I-like receptor signaling pathway Toll-like receptor signaling pathway 3.39E-33
Cell cycle Hematopoietic cell lineage 8.26E-33
Cell cycle Jak-STAT signaling pathway 1.08E-31
  1. The regulatory relationship is gene set 1 regulates gene set 2.