Table 3 Top 10 most significant co-membership edges in the KEGG co-membership gene set network.
From: A method for developing regulatory gene set networks to characterize complex biological systems
Gene set 1 name | Gene set 2 name | P-value |
|---|---|---|
Dilated cardiomyopathy | Hypertrophic cardiomyopathy (HCM) | 2.9E-134 |
Oxidative phosphorylation | Parkinson's disease | 5E-132 |
Huntington's disease | Parkinson's disease | 2.2E-124 |
Alzheimer's disease | Parkinson's disease | 8.9E-113 |
Drug metabolism - cytochrome P450 | Metabolism of xenobiotics by cytochrome P450 | 2.5E-110 |
Alzheimer's disease | Huntington's disease | 1.5E-106 |
Alzheimer's disease | Oxidative phosphorylation | 1.5E-101 |
Huntington's disease | Oxidative phosphorylation | 1.02E-96 |
Pathways in cancer | Small cell lung cancer | 2.94E-91 |
Arrhythmogenic right ventricular cardiomyopathy (ARVC) | Hypertrophic cardiomyopathy (HCM) | 1E-89 |