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Table 5 Top 10 highest out-degree centrality and In-degree centrality of the KEGG exclusive R-GSN.

From: A method for developing regulatory gene set networks to characterize complex biological systems

Name DC (out) Name DC (in)
Cell cycle 0.54 Cell cycle 0.24
p53 signaling pathway 0.44 Hematopoietic cell lineage 0.21
TGF-beta signaling pathway 0.37 Cytokine-cytokine receptor interaction 0.20
Bladder cancer 0.32 Systemic lupus erythematosus 0.17
Small cell lung cancer 0.25 Leishmania infection 0.17
Chronic myeloid leukemia 0.24 Basal cell carcinoma 0.17
Jak-STAT signaling pathway 0.24 Cell adhesion molecules (CAMs) 0.17
Huntington's disease 0.24 Graft-versus-host disease 0.17
Non-small cell lung cancer 0.23 Viral myocarditis 0.16
Wnt signaling pathway 0.22 p53 signaling pathway 0.15