Table 6 Top 10 AD related gene sets arranged by p-value.
From: A method for developing regulatory gene set networks to characterize complex biological systems
Gene set name | Collection | Size | AD genes | P-value |
|---|---|---|---|---|
Genes involved in Lipid digestion, mobilization, and transport | Reactome | 46 | 16 | 2.60794E-13 |
Alzheimer's disease | KEGG | 169 | 28 | 3.33483E-13 |
lipid transport | GO Biological Process | 28 | 13 | 5.6133E-13 |
Genes involved in Lipoprotein metabolism | Reactome | 28 | 13 | 5.6133E-13 |
apoptotic process | GO Biological Process | 431 | 42 | 3.80595E-11 |
programmed cell death | GO Biological Process | 432 | 42 | 4.09448E-11 |
Genes involved in Metabolism of lipids and lipoproteins | Reactome | 478 | 44 | 8.10901E-11 |
Genes involved in Chylomicron-mediated lipid transport | Reactome | 16 | 9 | 2.51488E-10 |
cell development | GO Biological Process | 577 | 48 | 3.3663E-10 |
regulation of apoptotic process | GO Biological Process | 341 | 34 | 1.66543E-09 |