Reference-free inference of tumor phylogenies from single-cell sequencing data

BMC Genomics

Table 4 Results of permutation tests to assess phylogenies.

k-mer	Test Statistic	Distribution mean, sv	p-value
5-mer	0.6484	1, 0.0048	≤0.0001
10-mer	0.7333	1, 0.0058	≤0.0001
15-mer	0.6196	0.99, 0.0058	≤0.0001
20-mer	0.8266	1, 0.0049	≤0.0001

Column 2 is the test statistic that served to capture how well cells from the same stage of progression cluster. Column 3 describes null distribution characteristics derived from permutation testing. Column 4 is the probability of occurrence of the test statistic in the null.

ISSN: 1471-2164