Figure 5

Dependence of the ratio of the known pharmacological targets among potential target genes on the knockout effect value $R_{all}^T$. Black line shows the ratio of known targets, blue histogram displays the distribution of the knockout effect values $R_{all}^T$. Presented are results for STRING gene network. Presented ratio approaches 1.0 at the right tail of the distribution corresponding to a small proportion of genes with the highest predicted knockout effect values.