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Table 1 Knockout effect values R s T of 8 top target genes on expression of objective genes involved in "apoptotic process" GO category.

From: Prediction of tissue-specific effects of gene knockout on apoptosis in different anatomical structures of human brain

Brain structures UBC * RAC1 * PTPN11 CDC42 * FYN * LAT2 CTNNB1 * GRB2
Whole brain** 105.0 / 0.95 48.4 / 0.44 31.3 / 0.28 29.3 / 0.27 27.5 / 0.25 26.5 / 0.24 26.3 / 0.24 24.3 / 0.22
Cerebellum 110.2 / 1.00 50.8 / 0.46 30.2 / 0.27 32.6 / 0.30 30.0 / 0.27 26.2 / 0.24 29.9 / 0.27 26.5 / 0.24
Pons 104.5 / 0.95 49.3 / 0.45 31.3 / 0.28 32.6 / 0.30 27.0 / 0.25 28.7 / 0.26 25.0 / 0.23 22.9 / 0.21
Thalamus 102.5 / 0.93 49.8 / 0.45 31.8 / 0.29 32.5 / 0.29 28.0 / 0.25 27.4 / 0.25 26.3 / 0.24 23.2 / 0.21
Hypothalamus 103.1 / 0.94 48.9 / 0.44 30.8 / 0.28 31.6 / 0.29 27.2 / 0.25 27.5 / 0.25 28.1 / 0.25 23.5 / 0.21
Basal ganglia 104.2 / 0.95 48.5 / 0.44 33.1 / 0.30 28.7 / 0.26 26.6 / 0.24 28.3 / 0.26 26.9 / 0.24 24.0 / 0.22
Amygdala 103.8 / 0.94 47.2 / 0.43 31.9 / 0.29 29.1 / 0.26 28.0 / 0.25 27.1 / 0.25 27.6 / 0.25 24.1 / 0.22
Hippocampus 103.8 / 0.94 51.2 / 0.46 31.8 / 0.29 31.2 / 0.28 29.3 / 0.27 26.4 / 0.24 28.3 / 0.26 25.6 / 0.23
Cingulate gyrus 105.7 / 0.96 46.9 / 0.43 30.8 / 0.28 27.2 / 0.25 27.1 / 0.25 25.1 / 0.23 24.7 / 0.22 23.9 / 0.22
Temporal lobe 105.5 / 0.96 46.7 / 0.42 30.9 / 0.28 26.6 / 0.24 26.9 / 0.24 25.2 / 0.23 24.8 / 0.23 24.6 / 0.22
Parietal lobe 105.2 / 0.95 47.0 / 0.43 31.0 / 0.28 26.7 / 0.24 26.6 / 0.24 25.2 / 0.23 24.7 / 0.22 24.3 / 0.22
Frontal lobe 106.0 / 0.96 47.3 / 0.43 30.9 / 0.28 27.0 / 0.25 26.5 / 0.24 25.5 / 0.23 24.2 / 0.22 24.4 / 0.22
Occipital lobe 105.7 / 0.96 46.9 / 0.43 31.6 / 0.29 26.2 / 0.24 26.6 / 0.24 25.2 / 0.23 24.7 / 0.22 24.6 / 0.22
  1. Each cell contains original R s T value and R s T divided by maximum of R s T along all structures all genes, separated by a slash.
  2. * target genes involved in "apoptotic process" GO category
  3. ** R a l l T