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Table 2 Target genes with highest RankSpec values for different anatomical structures of the brain.

From: Prediction of tissue-specific effects of gene knockout on apoptosis in different anatomical structures of human brain

Structure Rank 1 2 3 4 5 6 7 8 9 10
cerebellum NR3C1* PAN2 CYTSA DPYSL2 GABRB3* GABRG2 NPM1* ABL2* ACAT2 PITPNA
pons FOXA2 ESR1* PPARG* NR1D2 ESRRG NTN1* UNC5B* THRA* NR4A2* FOXO1*
thalamus DPYSL2 FOXA2 FOXO1* PITPNA CRMP1 PTGDS RORA CDK5* DPYSL4 MCAT
hypothalamus FOXA2 FOXO1* NFATC1 POMC NR2F2 NKX2-2 TBXA2R TACR2 FZD10 NTS
basal ganglia FOXO1* FOXA2 TPM1 SYN1 GAD2 MCM7 LRP6* ACTN2* MCM3 SST*
amygdala MYB NPY1R NR2F2 NPY PNOC PDYN ZNF32 ATF1 RGS7 FOXO1*
hippocampus DPYSL2 CRMP1 PRKCA* CDK5* PA2G4* DCC* NOP58 DPYSL4 ERBB2 WNT3A*
cingulate gyrus SQSTM1* AES* NEDD4L PITPNA ADCY2 SHC2 BTRC NTRK2* ZFPM1 MEF2C*
temporal lobe AES* ADCY2 SQSTM1* NEDD4L KIDINS220 STAT6 SHC2 NTRK2* MEF2C* CCK*
parietal lobe AES* STAT6 SQSTM1* ADCY2 KIDINS220 NEDD4L MEF2C* RPF1 ZFPM1 CCK*
frontal lobe SQSTM1* AES* NEDD4L ADCY2 SHC2 BTRC STAT6 MEF2C* TRAF3* ECSIT
occipital lobe AES* ERBB4* UBE2D2 MEF2C* ADRBK1 RPF1 DNM1 PTTG1 PRKCB* KIDINS220
  1. * target genes involved in "apoptotic process" GO category