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Table 5 Results of the identification of brain structures of the left hemisphere characterized by the difference between regulatory potential for H.s. d. and H. s. n. miRNAs expressed in neural tissues and having substitutions shared with known human polymorphisms.

From: The evolution of Homo sapiens denisova and Homo sapiens neanderthalensis miRNA targeting genes in the prenatal and postnatal brain

AHBA
Struct. ID
*
Structure description. ID ** p,
H. s. d.
p,
H. s. n.
Cohen's d,
H. s. d.
Cohen's d,
H. s. n.
(Cohen's d, H. s. d.)
-
(Cohen's d, H. s. n.)
4060 lateral orbital g. 0.00194 0.00816 5.92943 5.18602 0.74341
4288 putamen 0.0018 0.00634 6.03981 5.29693 0.74288
4258 dentate g. 0.00156 0.0045 6.18038 5.55627 0.62411
4901 inferior rostral g. 0.0045 0.0084 5.59337 5.12814 0.46523
4193 lingual g., peristriate 0.00268 0.00618 5.78555 5.32347 0.46208
4187 cuneus, striate 0.00474 0.00956 5.50591 5.04395 0.46196
4151 inferior temporal g., b. of mts 0.0042 0.00632 5.60432 5.29836 0.30596
4194 lingual g., striate 0.00714 0.00878 5.28597 5.12021 0.16576
4160 fusiform g., b. of cos 0.00622 0.00794 5.32299 5.17916 0.14383
4417 lateral group of nuclei, ventral division 0.00708 0.00514 5.27528 5.39697 -0.12169
4256 CA3 field 0.00958 0.00798 5.06621 5.22156 -0.15535
4169 transverse gyri 0.00936 0.00686 5.12785 5.29476 -0.16691
4282 body of caudate nucleus 0.00672 0.00534 5.25194 5.42113 -0.16919
4012 precentral g., b. of the precentral sulcus 0.0064 0.00446 5.29517 5.51095 -0.21578
4244 parahippocampal g., lateral b. 0.00688 0.00454 5.31264 5.53652 -0.22388
4186 cuneus, peristriate 0.00386 0.00274 5.64365 5.88129 -0.23764
4150 inferior temporal g., lateral b. 0.00776 0.00522 5.21501 5.45297 -0.23796
4106 supramarginal g., superior b. 0.00518 0.00342 5.46435 5.70277 -0.23842
4088 postcentral g., superior lateral aspect 0.0024 0.0015 5.93668 6.17562 -0.23894
4121 precuneus, inferior lateral b. 0.004 0.0023 5.65682 5.89645 -0.23963
4166 Heschl's g. 0.00858 0.00516 5.19857 5.44275 -0.24418
4013 precentral g., superior lateral aspect 0.00452 0.00298 5.55536 5.80945 -0.25409
4015 precentral g., b. of the central sulcus 0.00814 0.00564 5.16805 5.42259 -0.25454
4120 precuneus, superior lateral b. 0.00246 0.00182 5.89955 6.15638 -0.25683
4245 parahippocampal g., b. of the cos 0.00672 0.00426 5.31989 5.58364 -0.26375
4223 cingulate g., frontal pt., superior b. 0.0052 0.00352 5.41984 5.68604 -0.2662
4048 g. rectus 0.00998 0.00646 5.01861 5.28996 -0.27135
4074 paracentral lobule, anterior pt., inferior b. 0.0042 0.00242 5.61742 5.89182 -0.2744
4113 angular g., superior b. 0.00912 0.00522 5.10417 5.38524 -0.28107
4280 head of caudate nucleus 0.00482 0.00302 5.49717 5.78461 -0.28744
4114 angular g., inferior b. 0.00686 0.00394 5.33423 5.6244 -0.29017
4087 postcentral g., b. of the central sulcus 0.00414 0.00222 5.64523 5.93594 -0.29071
4030 middle frontal g., superior b. 0.0032 0.00166 5.79657 6.08899 -0.29242
4270 long insular gyri 0.0097 0.00618 5.07045 5.36942 -0.29897
4014 precentral g., inferior lateral aspect 0.00318 0.00174 5.80203 6.10501 -0.30298
4200 occipito-temporal g., superior b. 0.00542 0.00314 5.44127 5.74428 -0.30301
4255 CA2 field 0.00338 0.0016 5.78178 6.08596 -0.30418
4273 short insular gyri 0.00502 0.0029 5.47924 5.79333 -0.31409
4099 supraparietal lobule, inferior b. 0.00482 0.00234 5.56715 5.88285 -0.3157
4045 inferior frontal g., orbital pt. 0.00272 0.00138 5.81445 6.1365 -0.32205
4039 Inferior frontal g., triangular pt. 0.00808 0.00528 5.16319 5.49488 -0.33169
4230 cingulate g., parietal pt., superior b. 0.00918 0.00546 5.13338 5.46665 -0.33327
4159 fusiform g., lateral b. 0.00336 0.00222 5.69632 6.03013 -0.33381
4023 superior frontal g., medial b. 0.00146 0.0007 6.19956 6.53647 -0.33691
4136 superior temporal g., inferior b. 0.00402 0.0018 5.66885 6.0067 -0.33785
4031 middle frontal g., inferior b. 0.00106 0.00058 6.29966 6.63933 -0.33967
4208 inferior occipital g., inferior b. 0.0017 0.00084 6.10349 6.44887 -0.34538
4251 subiculum 0.00486 0.00248 5.51224 5.8579 -0.34566
4073 paracentral lobule, anterior pt., superior b. 0.00522 0.0031 5.46017 5.81365 -0.35348
4079 frontal operculum 0.00502 0.0028 5.49085 5.84766 -0.35681
4149 inferior temporal g., b. of the its 0.00308 0.00176 5.82221 6.1795 -0.35729
4257 CA4 field 0.00612 0.00322 5.37575 5.73712 -0.36137
4215 superior occipital g., inferior b. 0.00876 0.00438 5.16436 5.5294 -0.36504
4063 subcallosal g. 0.00762 0.00424 5.24311 5.61246 -0.36935
4214 superior occipital g., superior b. 0.0035 0.00216 5.64522 6.01907 -0.37385
4143 middle temporal g., inferior b. 0.00444 0.00228 5.57522 5.95362 -0.3784
4207 inferior occipital g., superior b. 0.00632 0.00364 5.26928 5.65709 -0.38781
4051 medial orbital g. 0.00214 0.00096 5.9903 6.39314 -0.40284
4898 superior rostral g. 0.00612 0.00272 5.39109 5.80014 -0.40905
4098 supraparietal lobule, superior b. 0.00442 0.00198 5.63525 6.04788 -0.41263
4089 postcentral g., inferior lateral aspect 0.00762 0.00398 5.25268 5.67386 -0.42118
4107 supramarginal g., inferior b. 0.00668 0.00342 5.34353 5.7746 -0.43107
4178 planum polare 0.0065 0.00232 5.33903 5.77072 -0.43169
4224 cingulate g., frontal pt., inferior b. 0.00554 0.00254 5.42489 5.86867 -0.44378
4090 postcentral g., b. of the posterior central sulcus 0.00486 0.00206 5.53829 5.99888 -0.46059
4024 superior frontal g., lateral b. 0.00074 0.00022 6.59581 7.06305 -0.46724
4158 fusiform g., b. of the its 0.00142 0.00038 6.22982 6.69803 -0.46821
4201 occipito-temporal g., inferior b. 0.00284 0.00124 5.76999 6.2488 -0.47881
4142 middle temporal g., superior b. 0.00698 0.00336 5.26624 5.76073 -0.49449
  1. * - For each target brain structure, the following data are provided: (1) the AHBA ID and (2) its description; (3) and (4) p, the probability of observing L k r a n d L k r a n d Q by random chance using H. s. d. and H. s. n. miRNA with known human polymorphisms expressed in central nervous system tissues; (5) and (6) the Cohen's d statistic of the difference between the L krand and L k r a n d Q value distributions for H. s. d. and H. s. n. miRNAs with known human polymorphisms expressed in central nervous system tissues; (7) the difference between these Cohen's d statistics.
  2. ** - g., gyrus; b., bank; pt., part.