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Table 4 The parameter estimates for Model 3.

From: Analysis of functional importance of binding sites in the Drosophila gap gene network model

Name

Hb

Kr

Gt

Kni

Bcd

Cad

Tll

Hkb

hb

−380.96

−969.47

−524.70

−362.00

634.59

31.17

17507.75

−31.00

Kr

−260.42/4243.26 (10.74)

−280.98

−1862.02

−2151.97

208.23

5019.33

−492.89

−13546.80

gt

−2275.97

−438.00

4969.40

−148.88

31.56

603.56

−452.08

−956.16

kni

−118.28

−262.29

−2104.13

769.61

13.67

6520.02

−6535.77

−3347.14

K

0.052258

0.009202

0.052464

0.035870

0.047500

0.031079

0.044106

0.046209

ω

1.000000

2.115275

1.049995

5.152606

1.000000

1.000000

4.992530

2.285720

Ï„

5.8

4.0

1.0

6.8

Nmax (q BTM ):

2 (9.5 × 10−6)

Range:

142

  1. Rows 2-5 present regulatory parameters Tab for target genes while columns correspond to TFs. The action of Hb on Kr is characterized by two coefficients for intensities less and greater than the threshold value (given in brackets). K, ω and τ are affinity, cooperativity and delay constants respectively. N max and q BTM are the number of activators interacting with the BTM and the BTM affinity constant respectively. Range is the range for repressor action in bps.