Figure 4

Subclonal inference results of sample MB-106. (a) The subclonal cellular prevalences estimated by MixClone, the tumor purities estimated by PyLOH, THetA [11], and the tumor purities estimated by ABSOLUTE [20] reported in [12] of sample MB-106. Each blue dot represents a segment. The x-axis is the estimated absolute copy number of the segment, and the y-axis is the estimated subclonal cellular prevalence of the segment. (b) The five log-likelihoods of MB-106 under different number of subclonal populations.