Computational steps for the identification of miRNA-mRNA regulatory modules. 1) Collection of miRNA expression profile data set. 2) Discovery of discriminatory rules from the miRNA expression data set using our rule discovery algorithm. 3) Construction of a selected and relevant mRNA expression data set. 4) Discovery of discriminatory rules from the relevant mRNA data set. 5) Identification of candidate miRNA-mRNA regulatory modules by combining the miRNAs and mRNAs in the discovered rules.