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Figure 2 | BMC Genomics

Figure 2

From: Integrated analyses to reconstruct microRNA-mediated regulatory networks in mouse liver using high-throughput profiling

Figure 2

TF-miRNA regulatory network. A total of 240 TF-miRNA interactions involving 40 TFs and 65 DEmiRs were collected for this network, with transcription factor Spi1 and Ctcf binding directly to the promoters of numerous miRNAs. Most of the UPmiRs (41 miRNAs) regulated by Ctcf and Spi1 are located in Chr12qF1. The octagonal nodes represent the transcription factors (TF) and the V-shaped nodes correspond to the miRNAs, while the nodes marked by the blue border represent the miR-122 targets. The up-regulated miRNAs/TFs are marked in red; down-regulated miRNAs/TFs are marked in green; TFs showing no differential expression are marked in grey.

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BMC Genomics

ISSN: 1471-2164

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