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Table 3 Functional analysis of 204 down-regulated target genes of UPmiRs and 295 up-regulated target genes of DNmiRs in IPA "Diseases and Functions".

From: Integrated analyses to reconstruct microRNA-mediated regulatory networks in mouse liver using high-throughput profiling

Diseases and Functions

UPmiRs

DNmiRs

 

pvalue

Count

pvalue

Count

Lipid Metabolism

3.85E-06

22

  

Cellular Growth and Proliferation

9.18E-06

26

5.17E-10

77

Connective Tissue Disorders

1.12E-04

11

  

Energy Production

5.59E-04

5

  

Metabolic Disease

8.11E-04

8

  

RNA Post-Transcriptional Modification

1.10E-03

3

  

Nervous System Development and Function

1.57E-03

25

5.27E-28

61

Tissue Development

1.60E-03

34

6.33E-29

96

Cell-To-Cell Signaling and Interaction

1.64E-03

12

6.33E-29

54

Cell Death and Survival

4.27E-03

12

4.85E-24

105

Cellular Assembly and Organization

4.68E-03

17

6.33E-29

65

Cellular Movement

6.92E-03

6

4.52E-09

58

Cell Cycle

1.06E-02

4

2.28E-07

32

Organismal Survival

1.82E-11

99

Total number of UPmiR-targets: 57

Total number of DNmiR-targets: 168