Figure 1

Aberrant adjacencies of genomic regions. Thick vertical lines represent chromosomes in the reference genome, circles represent breakpoints, small black boxes represent NGS reads, solid curved lines represent paired-reads, dashed curved lines represent split reads, and thin solid oblique lines represent aberrant adjacencies. Aberrant adjacencies are detected by using two types of NGS reads abnormally mapped to the reference genome: discordant pairs (three pairs from above), and split reads (two pairs from below). Yasuda and Miyano Page 11 of 11