Pinpointing disease genes through phenomic and genomic data fusion

BMC Genomics

Table 1 Coverage and accuracy of individual data sources.

Data source	Coverage		Linkage Interval			Random Control
	Genes	Ratio (%)	TOP (%)	MRR (%)	AUC (%)	TOP (%)	MRR (%)	AUC (%)
gexp	12,462	61.31	49.43	23.99	76.47	50.32	23.62	76.87
gobp	14,465	71.16	77.47	11.94	88.56	78.48	11.18	89.35
kegg	6,468	31.82	52.98	15.27	85.85	53.73	14.20	86.97
pseq	14,196	69.84	51.21	18.55	82.12	51.85	17.76	82.96
pfam	17,091	84.08	60.87	15.86	84.83	62.25	14.52	86.25
strg	12,432	61.16	72.99	12.64	88.04	73.60	11.84	88.90
tsfc	20,314	99.94	52.13	26.38	74.97	51.90	26.19	74.48
all	20,327	100.0	79.65	9.45	91.37	81.85	9.94	90.48

Results are obtained according to the leave-one-out cross-validation experiments.

ISSN: 1471-2164