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Table 1 The top 20 biological processes assigned to the development-regulating HOTAIR by LncRNA2Function.

From: LncRNA2Function: a comprehensive resource for functional investigation of human lncRNAs based on RNA-seq data

GO term Background frequency Sample frequency P-value Corrected
P-value
System development 3253/20447 38/74 1.63E-12 2.37E-08
Anatomical structure morphogenesis 1884/20447 28/74 2.45E-11 7.10E-08
Tissue development 1183/20447 23/74 1.33E-11 7.10E-08
Embryonic skeletal system development 120/20447 10/74 1.73E-11 7.10E-08
Anatomical structure development 3717/20447 39/74 2.07E-11 7.10E-08
Skeletal system development 388/20447 14/74 1.01E-10 2.44E-07
Organ morphogenesis 790/20447 18/74 2.89E-10 4.73E-07
Multicellular organismal development 3830/20447 38/74 2.56E-10 4.73E-07
Developmental process 4248/20447 40/74 2.93E-10 4.73E-07
Organ development 2271/20447 29/74 3.63E-10 5.27E-07
Skeletal system morphogenesis 189/20447 10/74 1.54E-09 1.72E-06
Multicellular organismal process 5336/20447 44/74 1.39E-09 1.72E-06
Single-multicellular organism process 5125/20447 43/74 1.51E-09 1.72E-06
Extracellular matrix organization 204/20447 10/74 3.23E-09 3.28E-06
Extracellular structure organization 205/20447 10/74 3.39E-09 3.28E-06
Head development 52/20447 6/74 3.26E-08 2.96E-05
Embryonic skeletal system morphogenesis 91/20447 7/74 3.86E-08 3.30E-05
Single-organism developmental process 3161/20447 31/74 4.39E-08 3.54E-05
Chordate embryonic development 557/20447 13/74 9.05E-08 6.57E-05
Embryo development ending in birth or egg hatching 564/20447 13/74 1.05E-07 7.23E-05