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Table 3 The top 20 biological processes assigned to the AIDS-related lncRNA HCP5 by LncRNA2Function.

From: LncRNA2Function: a comprehensive resource for functional investigation of human lncRNAs based on RNA-seq data

GO term Background frequency Sample frequency P-value Corrected
P-value
Immune system process 1581/20447 208/458 1.0E-109 3.49E-105
Immune response 867/20447 148/458 1.57E-90 2.70E-86
Defense response 968/20447 144/458 2.37E-79 2.72E-75
Regulation of immune system process 879/20447 131/458 1.16E-71 9.95E-68
Regulation of immune response 527/20447 105/458 9.62E-70 6.62E-66
Response to stimulus 6195/20447 312/458 9.35E-64 5.36E-60
Cell activation 557/20447 89/458 3.11E-50 1.53E-46
Leukocyte activation 344/20447 73/458 5.00E-50 2.15E-46
Regulation of response to stimulus 2379/20447 173/458 1.23E-48 4.72E-45
Positive regulation of immune system process 522/20447 84/458 1.39E-47 4.77E-44
Response to stress 2747/20447 181/458 4.76E-45 1.26E-41
Signal transduction 3612/20447 205/458 4.25E-42 1.04E-38
Positive regulation of immune response 331/20447 63/458 4.17E-40 9.56E-37
Cellular response to stimulus 4596/20447 231/458 5.11E-40 1.10E-36
Lymphocyte activation 276/20447 58/458 1.81E-39 3.66E-36
Innate immune response 474/20447 72/458 6.13E-39 1.17E-35
Positive regulation of response to stimulus 1154/20447 106/458 6.43E-37 1.16E-33
T cell activation 176/20447 46/458 5.40E-36 9.28E-33
Single organism signaling 4081/20447 208/458 1.23E-35 1.92E-32
Immune response-regulating signaling pathway 218/20447 49/458 6.76E-35 1.01E-31