Table 2 Statistical analyses for identification of the most discriminating endonuclease for molecular serotyping.
From: Revisitingmolecular serotyping of Streptococcus pneumoniae
Enzyme | Number of indistinguishable pairs of serotypes | Specificity for serotyping | Specificity for serogrouping | Median pairwise distances between cps-RFLP patterns | Mean pairwise distance between cps-RFLP patterns ± Standard Deviation | Median significantly different when compared to XhoII (p < 0.05) |
|---|---|---|---|---|---|---|
BslFI | 17 | 66.3% | 85.8% | 29.6 | 31.6 ± 15.7 | Yes |
Eco57MI | 23 | 56.5% | 89.1% | 30.5 | 32.0 ± 15.2 | Yes |
HindII | 27 | 54.3% | 75% | 29.8 | 31.8 ± 16.0 | Yes |
HinfI | 235 | 15.2% | 23.9% | 8.6 | 10.0 ± 6.4 | Yes |
StyI | 24 | 63% | 76% | 32.1 | 34.6 ± 18.4 | No |
XhoII | 11 | 76% | 100% | 32 | 34.5 ± 17.8 | - |