Figure 4
From: Memory acquisition and retrieval impact different epigenetic processes that regulate gene expression
Quantitative proteomic analysis of histone variants following contextual conditioning. A. Single ion chromatograms of peptides from core H2A (HLQLAIR, 453.780 m/z) or the H2AB variant (HLQLAVR). B. MS/MS spectra positively identifying the peak at 453.780 m/z as containing the HLQLAIR sequence (core H2A). C. MS/MS spectra identifying the peak at 466.772 m/z as containing the HLQLAVR sequence (H2AB). D. Quantification of histone variants following contextual conditioning. Values represent average normalized percentage (n = 4 per group) of the total for each variant for cage controls (CC) and contextual fear conditioning (FC). Statistical significance was determined using two-tailed t-tests.