MOST+: A de novo motif finding approach combining genomic sequence and heterogeneous genome-wide signatures

BMC Genomics

Table 4 Impact of parameter K on MOST/MOST+.

Mode	K	Time(s)	Motifs predicted	E-value
MOST	7	110.34	2	0.09
	8	111.85	5	4.87e-12
	9	133.06	5	6.35e-21
	10	448.22	5	1.02e-22
	11	2786.11	6	4.78e-20
MOST+	7	481	5	3.03e-05
	8	510	8	3.95e-13
	9	527	12	3.77e-21
	10	753	14	7.50e-27
	11	3244	6	1.07e-18

The test was run on mouse CTCF dataset (8 Mbp). Columns 3-5: 3) Times: running time under each word width K; 4) Motifs predicted: number of unique motifs found by each schema; and 5) E-value: the lowest e-value of alignments between a major motif found by each schema and motifs in mouse motif database.

ISSN: 1471-2164