Figure 5
From: Differential expression analysis of RNA sequencing data by incorporating non-exonic mapped reads
Statistical power of simulated RNA-seq data in different scenarios. Statistical power at pre-selected threshold (p = 0.05) in the scenarios of baseline background noise with 1.5 and 2 fold change, with 10% DEGs and 3 replicates per test group (a); Different background noises (b); Different background noises with highly expressed genes above 75% quantile of intensity (c); Different background noises and only lowly expressed genes below 25% quantile of intensity (d); Comparison with other statistical methods, under high background noise, with either 3 samples per test condition (e); or 6 samples per test condition (f). 3 replicates per test condition, with 10% DEGs and 1.5 fold change were used for (a, b, c, and d).