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Table 2 Area under the curve (AUC) of ROC in different background conditions (low, intermediate or high levels of non-exonic mapped reads) using DESeq and XBSeq, when comparing 3 or 6 replicates in each test group.

From: Differential expression analysis of RNA sequencing data by incorporating non-exonic mapped reads

  DESeq
Different background levels
XBSeq
Different background levels
Replicates per group Low Intermediate High Low Intermediate High
3 0.69 0.66 0.64 0.82 0.78 0.72
6 0.76 0.73 0.70 0.89 0.86 0.80
  1. Overall, XBSeq outperforms DESeq, on average in terms of AUC, by 0.11 and 0.12 for 3 and 6 replicates per group, respectively.
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