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Figure 1 | BMC Genomics

Figure 1

From: A translational bioinformatic approach in identifying and validating an interaction between Vitamin A and CYP19A1

Figure 1

Compound - CYP Regulator Network. The above figure depicts the overall network consisting of 868 interaction between the various compounds and CYP regulators that they affect. The density of the cluster is proportional to the number of compounds that influence its activity, and the nodes between clusters represents the compounds that influence more than one CYP regulator. The top 15 clusters were formed around ESR1, PXR, PPARalpha, LXRalpha, GCRalpha, LXRbeta, AHR, PPARgamma, PPARbeta, VDR, FXR, RXRbeta, LHR, CAR and TRbeta (the respective nodes are highlighted in red and interaction between retinoic acid and DAX1 is highlighted by the yellow rectangle).

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BMC Genomics

ISSN: 1471-2164

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