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Figure 5 | BMC Genomics

Figure 5

From: Systems analysis of gene ontology and biological pathways involved in post-myocardial infarction responses

Figure 5

Logical circuit of h_amiPathway. Logical circuits described the relationships between GO biological processes and the MI pathway. We used multiple input single output logical gates AND and OR, where the GOBP were the inputs and h_amiPathwaywere the outputs. The extracted network of MI identified five major GOBP terms, including tyrosine phosphorylation of STAT protein (ΔB79), coagulation (ΔB10), negative and positive regulation of blood coagulation (ΔB23 & ΔB30), and positive regulation of collagen metabolic process (ΔB32), required to activate the MI pathway. The labels next to the name of the GOBP terms corresponded to the legend in Figure 6.

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