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Table 3 Top 10 ranked cardiovascular diseases and its related risk factors.

From: A genome-wide systems analysis reveals strong link between colorectal cancer and trimethylamine N-oxide (TMAO), a gut microbial metabolite of dietary meat and fat

Diseases/traits Based on GWAS genetics (878) Diseases Based on OMIM genetics (4732)
Diseases/traits Ranking
(top%)
Diseases Ranking
(top%)
Obesity-related traits 0.11% Myocardial infarction, susceptibility to 0.23%
Coronary heart disease 0.80% Ventricular tachycardia 0.25%
HDL cholesterol 1.13% Diabetes mellitus, noninsulin-dependent 0.32%
Type 2 diabetes 1.48% Coronary artery disease, susceptibility to 0.51%
LDL cholesterol 1.82% LDL cholesterol level qt 0.66%
Total cholesterol 1.94% Hypercholesterolemia, familial 0.68%
Triglycerides 3.30% Microvascular complications of diabetes 0.69%
Lipid metabolism phenotypes 3.53% Atherosclerosis, susceptibility to 0.78%
Metabolic syndrome 3.64% Obesity, susceptibility to 1.88%
Cardiovascular disease risk factors 4.55% Diabetes mellitus, type 2, susceptibility
to
3.14%