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Table 6 Top ten ranked genetic pathways shared between TMAO and CRC.

From: A genome-wide systems analysis reveals strong link between colorectal cancer and trimethylamine N-oxide (TMAO), a gut microbial metabolite of dietary meat and fat

TMAO ∩ CRC (OMIM) TMAO ∩ CRC (GWAS) TMAO ∩ CRC (OMIM) ∩ CRC
(GWAS)
Pathways in cancer
Immune system
Neurotrophin signaling pathway Cell cycle
Wnt signaling
CMYB pathway
Adaptive immune system
MYC activpathway
MARK signaling pathway Hemostasis
Immune system
Cell cycle
Pathways in cancer
Metabolism of proteins
TCA cycle and respiratory electron transport
MYC activpathway
Adaptive immune system
WNT signaling
MAPK signaling pathway Metabolism of lipids and lipoproteins
Immune system
Cell cycle
Pathways in cancer
WNT signaling
Adaptive immune system
MYC activpathway
MAPK signaling pathway Chromosome maintenance Telomere maintenance
Metabolism of lipids and lipoproteins