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Table 3 Percentage of each types of regulatory regions overlapped with different human genomic regions

From: Disease-associated variants in different categories of disease located in distinct regulatory elements

 

Overlapping Coding Exon (bp)

Overlapping Upstream (bp)

Overlapping 3'-UTR (bp)

Overlapping 5'-UTR (bp)

Overlapping Introns (bp)

Overlapping Downstream (bp)

Overlapping Intergenic Regions (bp)

Transcription

318,864

1,033,885

235,904

793,623

948,521

202,588

1,747,482

promoter

(8.32%)

(26.97%)

(6.15%)

(20.7%)

(24.74%)

(5.23%)

(45.58%)

Transcription

275

443,003

12,826

8,301

4,351,818

326,034

7,628,892

enhancer

(0.002%)

(3.58%)

(0.1%)

(0.07%)

(35.14%)

(2.63%)

(61.6%)

Transcription

1,678,883

6,568,355

1,642,952

2,007,230

25,080,619

3,312,161

49,525,266

insulator

(2%)

(8.04%)

(2%)

(2.45%)

(30.7%)

(4.05%)

(60.6%)

Methylation

961,891

3,066,144

790,094

850,738

5,552,194

1,039,107

10,745,614

region

(4.93%)

(15.71%)

(4.04%)

(4.36%)

(28.45%)

(5.32%)

(55%)

Histone

19,836,913

65,289,808

27,693,911

13,261,068

901,286,244

69,178,945

1,820,842,829

modification region

(0.7%)

(2.32%)

(1%)

(0.47%)

(32%)

(2.46%)

(64.64%)

Chromatin

14,486,785

45,832,380

20,066,412

9,708,604

464,537,271

46,072,176

761,585,471

physical interaction regions

(1.12%)

(3.56%)

(1.6%)

(0.75%)

(36.05%)

(3.58%)

(59.1%)

DNA binding

5,252,509

22,329,204

6,553,411

5,567,759

130,492,231

14,945,226

224,621,692

sites of protein

(1.38%)

(5.87%)

(1.7%)

(1.46%)

(34.3%)

(3.93%)

(59.06%)

Open

6,309,327

22,046,177

6,966,217

5,626,301

131,734,716

15,003,875

229,306,915

chromatin regions (DNase

(1.63%)

(5.69%)

(1.8%)

(1.45%)

(34.02%)

(3.88%)

(59.23%)

I hypersensitive sites)

       

Open

4,896,207

18,119,824

6,098,267

4,612,397

137,079,859

12,725,401

290,428,922

chromatin regions by

(1.09%)

(4.03%)

(1.4%)

(1.02%)

(30.56%)

(2.84%)

(64.75%)

FAIRE-seq