From: Insights from GWAS: emerging landscape of mechanisms underlying complex trait disease
Protein category | #Proteins with a low impact missense mechanism | #Proteins with a high impact missense mechanism | #Proteins with a change in expression mechanism | #Proteins with a putative splicing mechanism | #Proteins with a direct splice mechanism |
---|---|---|---|---|---|
A | 4 | 3 | 24 | 3 | 2 |
B | 168 | 104 | 155 | 109 | 17 |
C | 219 | 77 | 121 | 116 | 14 |
D | 37 | 42 | 81 | 58 | 15 |