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Table 2 Number of proteins in each category of disease relevance for each mechanism.

From: Insights from GWAS: emerging landscape of mechanisms underlying complex trait disease

Protein category

#Proteins with a low impact missense mechanism

#Proteins with a high impact missense mechanism

#Proteins with a change in expression mechanism

#Proteins with a putative splicing mechanism

#Proteins with a direct splice mechanism

A

4

3

24

3

2

B

168

104

155

109

17

C

219

77

121

116

14

D

37

42

81

58

15