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Figure 2 | BMC Genomics

Figure 2

From: NET-GE: a novel NETwork-based Gene Enrichment for detecting biological processes associated to Mendelian diseases

Figure 2

Minimal connecting network for GO:0036018. A) Minimal connecting network extracted from STRING 9.2 (http://www.string-db.org) build for the Biological Process term GO:003601 (cellular response to erythropoietin). The seed genes, directly annotated with GO:0036018, are HGNC:MT2A, HGNC:KIT, HGNC:EPOR and HGNC:MT1X. The connecting genes HGNC:JAK2 and HGNC:IL6, recovered by the minimization procedure, are associated to GO:0019221 (cytokine-mediated signaling pathway). B) Relation between the reference GO term (GO:0036018) and the GO associated to the connecting genes (GO:0019221).

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BMC Genomics

ISSN: 1471-2164

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