Table 1 Comparison of paralogous CMT1A-REP sequence alignment with orthologous control sequences, together with results of the Sawyer-CpG permutation test for detecting the imprint of gene conversion. Significance at the 95% level is indicated in bold. Comparison of orthologous and paralogous sequence alignments
From: Gene conversion homogenizes the CMT1A paralogous repeats
Sequences | Length (bp) | Variant sites (at CpGs) | CpG frequency | SSUF | P value |
|---|---|---|---|---|---|
CMT1A-REPs | 23758 | 257 (73) | 0.0098 | 5220559 | 0.008 |
Chr.12 orthologs | 23584 | 275 (62) | 0.0067 | 4405300 | 0.058 |