Table 1 Use of ROC analysis for the selection of cut-off values for individual microarray experiments.
From: Defining signal thresholds in DNA microarrays: exemplary application for invasive cancer
Array 1 | Array 2 | ||||||
|---|---|---|---|---|---|---|---|
Threshold | Specificity [%] | Sensitivity [%] | % genes below threshold* | Threshold | Specificity [%] | Sensitivity [%] | % genes below threshold* |
0.010 | 0.0 | 100 | 0 | 0.005 | 0.0 | 100 | 0 |
0.030 | 1.8 | 100 | 0 | 0.010 | 2.5 | 100 | 0 |
0.040 | 13.4 | 100 | 0 | 0.015 | 9.3 | 100 | 0 |
a 0.057 | 49.7 | 99.7 | 0 | 0.020 | 30.5 | 100 | 0 |
0.060 | 52.7 | 99.6 | 1 | a 0.027 | 51.0 | 100 | 0 |
b 0.077 | 68.6 | 99.4 | 7 | 0.030 | 57.7 | 100 | 1 |
0.080 | 71.1 | 99.4 | 7 | b 0.031 | 58.6 | 100 | 1 |
0.100 | 81.3 | 99.0 | 17 | 0.040 | 75.4 | 99.9 | 12 |
0.120 | 86.8 | 98.2 | 26 | 0.050 | 89.9 | 99.8 | 20 |
0.140 | 90.0 | 97.7 | 36 | 0.060 | 93.9 | 99.6 | 29 |
0.170 | 94.9 | 96.5 | 44 | 0.062 | 94.9 | 99.6 | 31 |
d 0.180 | 95.6 | 96.1 | 44 | 0.064 | 95.6 | 99.9 | 33 |
c 0.192 | 96.6 | 95.8 | 47 | c 0.066 | 96.0 | 99.5 | 36 |
0.200 | 97.4 | 95.7 | 48 | d 0.090 | 98.1 | 98.5 | 43 |
0.300 | 98.6 | 92.8 | 65 | 0.100 | 99.1 | 98.3 | 45 |
0.400 | 99.5 | 89.9 | 77 | 0.110 | 100 | 97.6 | 48 |
0.500 | 100 | 85.0 | 79 | 0.200 | 100 | 92.0 | 65 |
0.700 | 100 | 74.7 | 83 | 0.500 | 100 | 85.7 | 81 |
1.000 | 100 | 56.6 | 89 | 0.800 | 100 | 72.4 | 90 |
1.500 | 100 | 28.7 | 95 | 1.000 | 100 | 50.8 | 94 |
2.000 | 100 | 19.4 | 98 | 1.500 | 100 | 17.1 | 97 |
3.000 | 100 | 10.2 | 98 | 2.000 | 100 | 7.7 | 98 |
5.000 | 100 | 5.4 | 99 | 2.500 | 100 | 2.9 | 98 |
10.000 | 100 | 1.2 | 100 | 3.000 | 100 | 2.1 | 99 |
12.000 | 100 | 0.0 | 100 | 5.000 | 100 | 0.0 | 100 |