Figure 2

A) Schematic intron-exon diagram of the zebrafish gnrh 3 gene The exons and introns are marked as boxes and lines, respectively. The intron lengths are shown underneath the lines. B) Exon lengths are shown above the mRNA sequence. The functional domains of the prepro polypeptide and untranslated regions (UTR) are marked. C) Post-translational cleavage of the signal peptide and GAP at the proteolytic cleavage site (GKR), generate the mature Gnrh3 decapeptide from the prepro polypeptide.