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Figure 3 | BMC Genomics

Figure 3

From: Gene trap mutagenesis of hnRNP A2/B1: a cryptic 3' splice site in the neomycin resistance gene allows continued expression of the disrupted cellular gene

Figure 3

Inheritance of the 1B4 provirus. Mice heterozygous for the 1B4 provirus were crossed and their progeny were analyzed by Southern blot analysis following Eco R1 digestion and hybridization to the 1B4 flanking sequence. (A) Representative Southern blot hybridization patterns for wild-type (+/+), heterozygous (+/-), and homozygous mutant (-/-) mice. (B) Inheritance of the 1B4 provirus follows a Mendelian distribution as assessed by the distribution of genotypes of progeny from intercrossing 1B4 heterozygotes.

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