Figure 6

Alignment of human, macaque, mouse and rat 7012 sequences. The sequenc es of predicted peptides for human (Hs), macaque (Mf), mouse (Mm) and rat (Rn) orthologues of 7012 were compared using AlignX. Portions of the human sequence were obtained from XP_059659, a peptide predicted from annotation of the human genome at NCBI. The macaque sequence was derived from Genbank entry BAB63112, the predicted translation product of a cDNA isolated from macaque testis. The mouse sequence was obtained by mapping the exon structure of the orthologous gene on the region of mouse chromosome 15. The rat coding sequence was constructed by assembling conserved exons on contigs RNOR01068092, RNOR01068093 and RNOR01068094 (Accession numbers AABR02034780 and AABR02122391). The sequence corresponding to the hamster clone obtained in this study is indicated with a dotted red underline in the human sequence.