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Figure 3 | BMC Genomics

Figure 3

From: TMC and EVER genes belong to a larger novel family, the TMC gene family encoding transmembrane proteins

Figure 3

Comparison of murine and pufferfish TMC gene structures Comparison of murine (Mm)(A) and pufferfish (Fr)(B) TMC gene structures. To compare and visualize the gene structures of TMC genes, the predicted coding sequences (depicted here with white boxes) were aligned. Gaps were introduced when required for appropriate comparison (illustrated as black boxes). Triangles mark positions where the coding sequence is interrupted by introns in the genome (intron locations). The triangles are colour-coded to reflect the degree of conservation of the intron locations among TMC subfamilies A, B, and C. Positions of introns conserved in all members of the TMC family are denoted by black triangles; blue, red and yellow triangles label positions of introns conserved within individual TMC subfamilies; orange, magenta and green triangles denote intron positions shared by members of two subfamilies; intron positions unique to a single family member are indicated by open black triangles. (C) Phylogenetic tree drawn based on the similarity of the gene structures of murine TMC genes restricted to the conserved region of the TMC proteins. The corresponding matrix of distances is shown in additional file 1.

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