Congruence of tissue expression profiles from Gene Expression Atlas, SAGEmap and TissueInfo databases

BMC Genomics

Table 1 r² values for Pearson correlations between PEM scores computed from Gene Expression Atlas (GEA), SAGEmap and TissueInfo expression profiles for six human tissue categories, for which data were available in the three databases.

	Tissue	TissueInfo vs. SAGEmap				GEA vs. SAGEmap				GEA vs. TissueInfo
	Genes^a	r ²	P^b	Signs^c	Genes^a	r ²	P^b	Signs^c	Genes^a	r ²	P^b	Signs^c
Brain	346	0.59	<0.01	92%	479	0.49	<0.01	84%	1431	0.43	<0.01	77%
Prostate	58	0.36	<0.01	76%	237	0.09	<0.01	59%	266	0.19	<0.01	63%
Vascular endothelium	13	0.29	0.6	92%	150	0.37	<0.01	73%	23	0.05	0.29	39%
Ovary	10	0.11	0.35	30%	175	0.03	0.2	49%	36	0.03	0.28	69%
Kidney	103	0.01	0.36	34%	140	0.00	0.78	50%	508	0.11	<0.01	55%
Pancreas	21	0.02	0.55	62%	141	0.00	0.59	48%	82	0.02	0.19	55%

^a Number of genes compared. SAGEmap and TissueInfo data were only used for genes whose PEM scores were significant by χ² test (P = 0.05), and only tags that could be mapped unambiguously to UniGene were used. ^b Two-tailed significance values for Pearson correlation coefficients. ^c Percentage of genes whose PEM scores have the same sign for the two methods being compared.

ISSN: 1471-2164