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Table 4 Top ten prostate-specific genes identified by integrated PEM scores from Gene Expression Atlas, SAGEmap and TissueInfo.

From: Congruence of tissue expression profiles from Gene Expression Atlas, SAGEmap and TissueInfo databases

%PEM a UniGene cluster LocusLink symbol Description and references
95% Hs.183752 MSMB beta microseminoprotein; synthesized by the epithelial cells of the prostate gland and secreted into the seminal plasma [77]
94% Hs.1852 ACPP prostatic acid phosphatase [78]
82% Hs.171995 KLK3 kallikrein 3; prostate specific antigen (PSA) [79]
73% Hs.78344 MYH11 smooth muscle-specific myosin heavy polypeptide 11 [80]
70% Hs.300772 TPM2 tropomyosin 2 (beta); binds actin [81]
55% Hs.195464 FLNA filamin A; binds actin [82]
54% Hs.75777 TAGLN transgelin; smooth muscle-specific actin binding protein [83]
53% Hs.262476 AMD1 S-adenosylmethionine decarboxylase 1; key enzyme in the synthesis of seminal polyamines such as spermine, spermidine [84]
53% Hs.9615 MYL9 myosin, smooth muscle-specific regulatory light polypeptide 9 [85]
48% Hs.179817 RDH11 androgen-regulated short-chain dehydrogenase/reductase 1 [86]
  1. a Prostate PEMGEAmax = 4.30, PEMSAGEMAPmax = 1.97, and PEMTISSUEINFOmax = 1.61